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Unveiling the Truth: Testosterone Replacement Therapy and Heart Risks

Hormone replacement therapy tends to be quite a polarizing healthcare subject. Over the years, there has been a lot of scrutiny surrounding testosterone replacement therapy (TRT) and its potential impact on heart health. This recent article published by CNN “Testosterone Replacement Therapy Doesn’t Raise Major Heart Risks” explores the truth behind hormone replacement therapy and its relationship to cardiovascular health.


Understanding Testosterone Replacement Therapy (TRT)
Testosterone is a hormone primarily responsible for the development of male sexual characteristics and plays a vital role in maintaining overall health in both men and women. However, as men age, their testosterone levels naturally decrease, leading to many symptoms such as low libido, extreme fatigue, weight gain, brain fog, and mood changes. To help remedy these issues, many men and women turn to testosterone replacement therapy to help them regain control of their health and to help them look and feel their best.

A New Study Unveils the Truth

According to older studies, men who received TRT were found to have a higher likelihood of experiencing cardiovascular events, including heart attacks and strokes. However, like any other scientific research, these studies have limitations. The studies were observational in nature, which in turn means it can’t establish a causal relationship between TRT and heart risks, but only an association. It is evident that further trials and research were needed to establish a definitive causal relationship between TRT and heart risks. A recent study published in the New England Journal of Medicine, found men who have low testosterone and have cardiovascular disease were not at an increased risk of cardiac events.

“This article confirms what I inform my patients regarding testosterone replacement therapy,” noted Dr. Sachin Shah, Medical Director of Advanced Anti-Aging when asked about the study.

While the article raises some concerns about TRT, it’s important to take a look at the results with a broader context of existing research. Previous studies on this topic have yielded mixed results; with some indicating an increased risk while others suggesting no significant association. 

It is imperative for individuals considering or undergoing testosterone replacement therapy to have open and honest discussions with their healthcare providers. This is why it’s crucial that doctors who prescribe hormone replacement do an in-depth blood analysis prior to prescribing. This helps uncover any pre-existing conditions that could potentially lead to more risks. This is an important step in the patient onboarding process, which helps determine if someone is a good candidate for TRT. 

 “As long as it is done under physician supervision, with the goal to improve wellness and overall health, TRT can be very helpful in achieving your goals,” Dr. Shah said.

At Advanced Anti-Aging, our testosterone replacement programs are individualized for each person and we are there every step of the way to get you started and on your way back to optimal health. Testosterone Replacement Therapy (TRT) and Bio-Identical Hormone Replacement Therapy (BHRT) are great options for getting back to feeling your best. Our patients choose what feels best for them. Some patients choose injections, whereas others may choose creams. Our programs are tailored JUST for you. To get started, visit our website or give our office a call.